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The Two-Species Model of transketolase explains donor substrate-binding, inhibition and heat-activation
We recently characterised a low-activity form of E. coli transketolase, TK(low), which also binds the cofactor thiamine pyrophosphate (TPP) with an affinity up to two-orders of magnitude lower than the previously known high TPP-affinity and high-activity form, TK(high), in the presence of Mg(2+). We...
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| Publicado no: | Sci Rep |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7057962/ https://ncbi.nlm.nih.gov/pubmed/32139871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61175-z |
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