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RUNX1 Mutations in the Leukemic Progression of Severe Congenital Neutropenia

Somatic RUNX1 mutations are found in approximately 10% of patients with de novo acute myeloid leukemia (AML), but are more common in secondary forms of myelodysplastic syndrome (MDS) or AML. Particularly, this applies to MDS/AML developing from certain types of leukemia-prone inherited bone marrow f...

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Vydáno v:Mol Cells
Hlavní autoři: Olofsen, Patricia A., Touw, Ivo P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Molecular and Cellular Biology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057833/
https://ncbi.nlm.nih.gov/pubmed/32041395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2020.0010
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