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Granulomatosis with polyangiitis in a patient treated with dabrafenib and trametinib for BRAF V600E positive lung adenocarcinoma

BACKGROUND: Dabrafenib and trametinib combination therapy is approved for the treatment of patients with BRAF V600E positive tumors including melanoma and lung cancer. The effect of BRAF and MEK inhibitors on the immune system is not fully understood although a number of case reports indicate autoim...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Dimou, Anastasios, Barron, Gregory, Merrick, Daniel T., Kolfenbach, Jason, Doebele, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057580/
https://ncbi.nlm.nih.gov/pubmed/32131760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6661-6
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