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Granulomatosis with polyangiitis in a patient treated with dabrafenib and trametinib for BRAF V600E positive lung adenocarcinoma

BACKGROUND: Dabrafenib and trametinib combination therapy is approved for the treatment of patients with BRAF V600E positive tumors including melanoma and lung cancer. The effect of BRAF and MEK inhibitors on the immune system is not fully understood although a number of case reports indicate autoim...

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Publicat a:BMC Cancer
Autors principals: Dimou, Anastasios, Barron, Gregory, Merrick, Daniel T., Kolfenbach, Jason, Doebele, Robert C.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057580/
https://ncbi.nlm.nih.gov/pubmed/32131760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6661-6
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