Glutaminase-1 (GLS1) inhibition limits metastatic progression in osteosarcoma

BACKGROUND: Osteosarcoma (OS) is a malignant bone tumor that often develops during the period of rapid growth associated with adolescence. Despite successful primary tumor control accompanied by adjuvant chemotherapy, death from pulmonary metastases occurs in approximately 30% of patients within 5 y...

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Publicat a:Cancer Metab
Autors principals: Ren, L., Ruiz-Rodado, V., Dowdy, T., Huang, S., Issaq, S. H., Beck, J., Wang, H., Tran Hoang, C., Lita, A., Larion, M., LeBlanc, A. K.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057558/
https://ncbi.nlm.nih.gov/pubmed/32158544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40170-020-0209-8
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