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Overcoming the blood-brain barrier with an implantable ultrasound device

Ultrasound-based blood-brain-barrier disruption enhances drug delivery to the brain. To bypass the thick human skull, an ultrasound that is implanted on a cranial window was developed, proven safe and feasible in a first-in-human trial. Next development steps aim for larger field of disruption, quan...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Sonabend, Adam M., Stupp, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057332/
https://ncbi.nlm.nih.gov/pubmed/31076548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-0932
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