ACTR-57. A PHASE 1/2 STUDY TO EVALUATE THE SAFETY AND EFFICACY OF BLOOD-BRAIN BARRIER (BBB) OPENING WITH A NINE-EMITTER IMPLANTABLE ULTRASOUND DEVICE IN RECURRENT GLIOBLASTOMA PATIENTS PRIOR TO CARBOPLATIN

The blood-brain barrier (BBB) limits penetration of systemically administered therapies to brain tumors and peritumoral tissue and may be responsible for the failure of numerous drugs in recent clinical trials for glioblastoma (GBM). Low intensity pulsed ultrasound (LIPU), with concomitant intraveno...

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Bibliografski detalji
Izdano u:Neuro Oncol
Glavni autori: Idbaih, Ahmed, Ducray, François, DeGroot, John, Stupp, Roger, Guyotat, Jacques, Lesniak, Maciej S, Sonabend, Adam, Weinberg, Jeffrey, Desseaux, Carole, Canney, Michael, Schmitt, Charlotte, Carpentier, Alexandre
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Adult Clinical Trials - Non-Immunologic
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847676/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.099
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