Design, Optimization, and Multisite Evaluation of a Targeted Next-Generation Sequencing Assay System for Chimeric RNAs from Gene Fusions and Exon-Skipping Events in Non–Small Cell Lung Cancer

Lung cancer accounts for approximately 14% of all newly diagnosed cancers and is the leading cause of cancer-related deaths. Chimeric RNA resulting from gene fusions (RNA fusions) and other RNA splicing errors are driver events and clinically addressable targets for non–small cell lung cancer (NSCLC...

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Publicado no:J Mol Diagn
Main Authors: Blidner, Richard A., Haynes, Brian C., Hyter, Stephen, Schmitt, Sarah, Pessetto, Ziyan Y., Godwin, Andrew K., Su, Dan, Hurban, Patrick, van Kempen, Léon C., Aguirre, Maria L., Gokul, Shobha, Cardwell, Robyn D., Latham, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057224/
https://ncbi.nlm.nih.gov/pubmed/30529127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2018.10.003
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