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METTL3 Facilitates Oral Squamous Cell Carcinoma Tumorigenesis by Enhancing c-Myc Stability via YTHDF1-Mediated m(6)A Modification

N(6)-Methyladenosine (m(6)A) is the most common internal modification of eukaryotic messenger RNA (mRNA) that occurred on the N(6) nitrogen of adenosine. However, the roles of m(6)A in oral squamous cell carcinoma (OSCC) are still elusive. Here, we investigate the function and mechanism of methyltra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Nucleic Acids
Hauptverfasser: Zhao, Wei, Cui, Yameng, Liu, Lina, Ma, Xiaozhou, Qi, Xiaoqian, Wang, Yue, Liu, Zihao, Ma, Shiqing, Liu, Jingwen, Wu, Jie
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057159/
https://ncbi.nlm.nih.gov/pubmed/32145676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.01.033
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