METTL3 Facilitates Oral Squamous Cell Carcinoma Tumorigenesis by Enhancing c-Myc Stability via YTHDF1-Mediated m(6)A Modification

N(6)-Methyladenosine (m(6)A) is the most common internal modification of eukaryotic messenger RNA (mRNA) that occurred on the N(6) nitrogen of adenosine. However, the roles of m(6)A in oral squamous cell carcinoma (OSCC) are still elusive. Here, we investigate the function and mechanism of methyltra...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Zhao, Wei, Cui, Yameng, Liu, Lina, Ma, Xiaozhou, Qi, Xiaoqian, Wang, Yue, Liu, Zihao, Ma, Shiqing, Liu, Jingwen, Wu, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057159/
https://ncbi.nlm.nih.gov/pubmed/32145676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.01.033
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