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De Novo Small Supernumerary Marker Chromosomes Arising From Partial Trisomy Rescue

Small supernumerary marker chromosomes (SMCs) are rare cytogenetic abnormalities. De novo small SMCs, particularly those combined with uniparental disomy (UPD), are assumed to result from incomplete trisomy rescue. Recently, a one-off cellular event designated as chromothripsis was reported as a mec...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Matsubara, Keiko, Yanagida, Kaede, Nagai, Toshiro, Kagami, Masayo, Fukami, Maki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056893/
https://ncbi.nlm.nih.gov/pubmed/32174976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00132
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