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Structural modification of aspirin to design a new potential cyclooxygenase (COX-2) inhibitors

Aspirin (Asp) is one of the most important and ancient member of nonsteroidal anti-inflammatory drugs (NSAID), commonly used in medication of fever, pain and inflammation. It can inhibit the synthesis of prostaglandin by blocking the cyclooxygenase (COX). Attempts have been taken to analyze aspirin...

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Bibliographic Details
Published in:In Silico Pharmacol
Main Authors: Uzzaman, Monir, Mahmud, Tareq
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056757/
https://ncbi.nlm.nih.gov/pubmed/32181121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40203-020-0053-0
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