Systematic characterization of chromatin modifying enzymes identifies KDM3B as a critical regulator in castration resistant prostate cancer

Androgen deprivation therapy (ADT) is the standard care for prostate cancer (PCa) patients who fail surgery or radiotherapy. While initially effective, the cancer almost always recurs as a more aggressive castration resistant prostate cancer (CRPC). Previous studies have demonstrated that chromatin...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Saraç, Hilal, Morova, Tunç, Pires, Elisabete, McCullagh, James, Kaplan, Anıl, Cingöz, Ahmet, Bagci-Onder, Tugba, Önder, Tamer, Kawamura, Akane, Lack, Nathan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056651/
https://ncbi.nlm.nih.gov/pubmed/31822799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-019-1116-8
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