pVACtools: a computational toolkit to identify and visualize cancer neoantigens: pVACtools: toolkit for tumor neoantigen characterization

Identification of neoantigens is a critical step in predicting response to checkpoint blockade therapy and design of personalized cancer vaccines. This is a cross-disciplinary challenge, involving genomics, proteomics, immunology, and computational approaches. We have built a computational framework...

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Udgivet i:Cancer Immunol Res
Main Authors: Hundal, Jasreet, Kiwala, Susanna, McMichael, Joshua, Miller, Christopher A., Xia, Huiming, Wollam, Alexander T., Liu, Connor J., Zhao, Sidi, Feng, Yang-Yang, Graubert, Aaron P., Wollam, Amber Z., Neichin, Jonas, Neveau, Megan, Walker, Jason, Gillanders, William E, Mardis, Elaine R., Griffith, Obi L., Griffith, Malachi
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056579/
https://ncbi.nlm.nih.gov/pubmed/31907209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-19-0401
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