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Best practices for bioinformatic characterization of neoantigens for clinical utility

Neoantigens are newly formed peptides created from somatic mutations that are capable of inducing tumor-specific T cell recognition. Recently, researchers and clinicians have leveraged next generation sequencing technologies to identify neoantigens and to create personalized immunotherapies for canc...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Richters, Megan M., Xia, Huiming, Campbell, Katie M., Gillanders, William E., Griffith, Obi L., Griffith, Malachi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6714459/
https://ncbi.nlm.nih.gov/pubmed/31462330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-019-0666-2
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