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ARRB1-promoted NOTCH1 degradation is suppressed by oncomiR miR-223 in T cell acute lymphoblastic leukemia
T cell acute lymphoblastic leukemia (T-ALL) is a type of aggressive leukemia with inferior prognosis. While activating mutations of NOTCH1 are observed in most T-ALL cases, these mutations alone are not sufficient to drive the full development of T-ALL. β-Arrestins (ARRBs) are versatile and multifun...
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| Yayımlandı: | Cancer Res |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7056567/ https://ncbi.nlm.nih.gov/pubmed/31822496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-1471 |
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