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Neuroprotective Peptide NAPVSIPQ Antagonizes Ethanol Inhibition of L1 Adhesion by Promoting the Dissociation of L1 and Ankyrin-G

BACKGROUND: Ethanol causes developmental neurotoxicity partly by blocking adhesion mediated by the L1 neural cell adhesion molecule. This action of ethanol is antagonized by femtomolar concentrations of the neuropeptide NAPVSIPQ (NAP), an active fragment of activity dependent neuroprotective peptide...

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Publicat a:Biol Psychiatry
Autors principals: Dou, Xiaowei, Lee, Jerry Y., Charness, Michael E.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056560/
https://ncbi.nlm.nih.gov/pubmed/31640849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2019.08.020
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