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Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly
The design and creation of synthetic genomes provides a powerful approach to understanding and engineering biology. However, it is often limited by the paucity of methods for precise genome manipulation. Here, we demonstrate the programmed fission of the Escherichia coli genome into diverse pairs of...
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| 發表在: | Science |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7056355/ https://ncbi.nlm.nih.gov/pubmed/31467221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay0737 |
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