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Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly
The design and creation of synthetic genomes provides a powerful approach to understanding and engineering biology. However, it is often limited by the paucity of methods for precise genome manipulation. Here, we demonstrate the programmed fission of the Escherichia coli genome into diverse pairs of...
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| Publié dans: | Science |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7056355/ https://ncbi.nlm.nih.gov/pubmed/31467221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aay0737 |
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