Nanoscale integrin cluster dynamics controls cellular mechanosensing via FAKY397 phosphorylation

Transduction of extracellular matrix mechanics affects cell migration, proliferation, and differentiation. While this mechanotransduction is known to depend on the regulation of focal adhesion kinase phosphorylation on Y397 (FAKpY397), the mechanism remains elusive. To address this, we developed a m...

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Publicat a:Sci Adv
Autors principals: Cheng, Bo, Wan, Wanting, Huang, Guoyou, Li, Yuhui, Genin, Guy M., Mofrad, Mohammad R. K., Lu, Tian Jian, Xu, Feng, Lin, Min
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7056303/
https://ncbi.nlm.nih.gov/pubmed/32181337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax1909
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