Disruption of Pressure-Induced Ca(2+) Spark Vasoregulation of Resistance Arteries, Rather Than Endothelial Dysfunction, Underlies Obesity-Related Hypertension

Obesity-related hypertension is one of the world’s leading causes of death and yet little is understood as to how it develops. As a result, effective targeted therapies are lacking and pharmacological treatment is unfocused. To investigate underlying microvascular mechanisms, we studied small artery...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Greenstein, Adam S., Kadir, Sharifah Zamiah Abdul Syed, Csato, Viktoria, Sugden, Sarah A., Baylie, Rachael A., Eisner, David A., Nelson, Mark T.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott, Williams & Wilkins 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055934/
https://ncbi.nlm.nih.gov/pubmed/31865779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13540
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