Immunotherapy with DNA vaccine and live attenuated rubella/SIV gag vectors plus early ART can prevent SIVmac251 viral rebound in acutely infected rhesus macaques

Anti-retroviral therapy (ART) has been highly successful in controlling HIV replication, reducing viral burden, and preventing both progression to AIDS and viral transmission. Yet, ART alone cannot cure the infection. Even after years of successful therapy, ART withdrawal leads inevitably to viral r...

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Veröffentlicht in:PLoS One
Hauptverfasser: Virnik, Konstantin, Rosati, Margherita, Medvedev, Alexei, Scanlan, Aaron, Walsh, Gabrielle, Dayton, Frances, Broderick, Kate E., Lewis, Mark, Bryson, Yvonne, Lifson, Jeffrey D., Ruprecht, Ruth M., Felber, Barbara K., Berkower, Ira
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055890/
https://ncbi.nlm.nih.gov/pubmed/32130229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228163
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