Inhibition of the oligosaccharyl transferase in Caenorhabditis elegans that compromises ER proteostasis suppresses p38-dependent protection against pathogenic bacteria

The oligosaccharyl transferase (OST) protein complex mediates the N-linked glycosylation of substrate proteins in the endoplasmic reticulum (ER), which regulates stability, activity, and localization of its substrates. Although many OST substrate proteins have been identified, the physiological role...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Jeong, Dae-Eun, Lee, Yujin, Ham, Seokjin, Lee, Dongyeop, Kwon, Sujeong, Park, Hae-Eun H., Hwang, Sun-Young, Yoo, Joo-Yeon, Roh, Tae-Young, Lee, Seung-Jae V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055741/
https://ncbi.nlm.nih.gov/pubmed/32130226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008617
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