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NKG2D–DAP10 signaling recruits EVL to the cytotoxic synapse to generate F-actin and promote NK cell cytotoxicity

Natural killer (NK) cells eliminate abnormal cells through the release of cytolytic granule contents. In this process, NK cells must adhere to target cells through integrin-mediated adhesion, which is highly dependent on the generation of F-actin. Ena/VASP-like (EVL) is an actin regulatory protein p...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Cell Sci
मुख्य लेखकों: Wilton, Katelynn M., Overlee, Brittany L., Billadeau, Daniel D.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Company of Biologists Ltd 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055393/
https://ncbi.nlm.nih.gov/pubmed/31235500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.230508
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