Very-long-chain fatty acid metabolic capacity of 17-beta-hydroxysteroid dehydrogenase type 12 (HSD17B12) promotes replication of hepatitis C virus and related flaviviruses

Flaviviridae infections represent a major global health burden. By deciphering mechanistic aspects of hepatitis C virus (HCV)-host interactions, one could discover common strategy for inhibiting the replication of related flaviviruses. By elucidating the HCV interactome, we identified the 17-beta-hy...

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Publicado no:Sci Rep
Main Authors: Mohamed, Bassim, Mazeaud, Clément, Baril, Martin, Poirier, Donald, Sow, Aïssatou Aïcha, Chatel-Chaix, Laurent, Titorenko, Vladimir, Lamarre, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055353/
https://ncbi.nlm.nih.gov/pubmed/32132633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-61051-w
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