Disruption of the kringle 1 domain of prothrombin leads to late onset mortality in zebrafish

The ability to prevent blood loss in response to injury is a conserved function of all vertebrates. Complete deficiency of the central clotting enzyme prothrombin has never been observed in humans and is incompatible with postnatal life in mice, thus limiting the ability to study its role in vivo. Z...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Grzegorski, Steven J., Hu, Zhilian, Liu, Yang, Yu, Xinge, Ferguson, Allison C., Madarati, Hasam, Friedmann, Alexander P., Reyon, Deepak, Kim, Paul Y., Kretz, Colin A., Joung, J. Keith, Shavit, Jordan A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055286/
https://ncbi.nlm.nih.gov/pubmed/32132579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60840-7
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak