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Verification of EZH2 as a druggable target in metastatic uveal melanoma
BACKGROUND: Hepatic metastasis develops in ~ 50% of uveal melanoma (UM) patients with no effective treatments. Although GNAQ/GNA11 mutations are believed to confer pathogenesis of UM, the underlying mechanism of liver metastasis remains poorly understood. Given that profound epigenetic evolution may...
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| Publicado no: | Mol Cancer |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7055080/ https://ncbi.nlm.nih.gov/pubmed/32127003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01173-x |
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