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Role of Parkin-mediated mitophagy in the protective effect of polydatin in sepsis-induced acute kidney injury
BACKGROUND: We have reported that polydatin (PD) alleviates mitochondrial dysfunction in rat models of sepsis-induced acute kidney injury (SI-AKI), but the mechanism is not well understood. Here, we investigated the role of Parkin-mediated mitophagy in the protective effects of PD in SI-AKI in mice....
में बचाया:
| में प्रकाशित: | J Transl Med |
|---|---|
| मुख्य लेखकों: | , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7055075/ https://ncbi.nlm.nih.gov/pubmed/32131850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02283-2 |
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