A novel TLR7 agonist as adjuvant to stimulate high quality HBsAg-specific immune responses in an HBV mouse model

BACKGROUND: The global burden of hepatitis B virus (HBV) infection in terms of morbidity and mortality is immense. Novel treatments that can induce a protective immune response are urgently needed to effectively control the HBV epidemic and eventually eradicate chronic HBV infection. METHODS: We des...

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Udgivet i:J Transl Med
Main Authors: Hu, Yunlong, Tang, Li, Zhu, Zhengyu, Meng, He, Chen, Tingting, Zhao, Sheng, Jin, Zhenchao, Wang, Zhulin, Jin, Guangyi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7055022/
https://ncbi.nlm.nih.gov/pubmed/32131853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02275-2
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