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TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity

We previously reported that synthetic or natural Toll-like receptor (TLR) 7/8 agonists present within dead cells enhanced cell-associated antigen presentation both in vitro and in vivo. Here, we investigated the immunopotency of different chemically synthesized TLR7/8 agonists, Resiquimod, Gardiquim...

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Hlavní autoři: Du, Jun, Wu, Zhiyuan, Ren, Shurong, Wei, Yong, Gao, Meihua, Randolph, Gwendalyn J., Qu, Chunfeng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031106/
https://ncbi.nlm.nih.gov/pubmed/20637759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.06.117
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