Role of angiopoietin-like protein 3 in sugar-induced dyslipidemia in rhesus macaques: suppression by fish oil or RNAi

Angiopoietin-like protein 3 (ANGPTL3) inhibits lipid clearance and is a promising target for managing cardiovascular disease. Here we investigated the effects of a high-sugar (high-fructose) diet on circulating ANGPTL3 concentrations in rhesus macaques. Plasma ANGPTL3 concentrations increased ∼30% t...

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Pubblicato in:J Lipid Res
Autori principali: Butler, Andrew A., Graham, James L., Stanhope, Kimber L., Wong, So, King, Sarah, Bremer, Andrew A., Krauss, Ronald M., Hamilton, James, Havel, Peter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053838/
https://ncbi.nlm.nih.gov/pubmed/31919051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000423
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