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Hepatic PLIN5 signals via SIRT1 to promote autophagy and prevent inflammation during fasting
Lipid droplets (LDs) are energy-storage organelles that are coated with hundreds of proteins, including members of the perilipin (PLIN) family. PLIN5 is highly expressed in oxidative tissues, including the liver, and is thought to play a key role in uncoupling LD accumulation from lipotoxicity; howe...
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| Publicado en: | J Lipid Res |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Biochemistry and Molecular Biology
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7053830/ https://ncbi.nlm.nih.gov/pubmed/31932301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000336 |
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