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Mathematical modeling and parameter estimation of levodopa motor response in patients with parkinson disease
Parkinson disease (PD) is characterized by a clear beneficial motor response to levodopa (LD) treatment. However, with disease progression and longer LD exposure, drug-related motor fluctuations usually occur. Recognition of the individual relationship between LD concentration and its effect may be...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7053720/ https://ncbi.nlm.nih.gov/pubmed/32126124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0229729 |
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