Functional heterogeneity of lymphocytic patterns in primary melanoma dissected through single-cell multiplexing

In melanoma, the lymphocytic infiltrate is a prognostic parameter classified morphologically into ‘brisk’, ‘non-brisk’ and ‘absent’ entailing a functional association that has never been proved. Recently, it has been shown that lymphocytic populations can be very heterogeneous, and that anti-PD-1 im...

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Veröffentlicht in:eLife
Hauptverfasser: Bosisio, Francesca Maria, Antoranz, Asier, van Herck, Yannick, Bolognesi, Maddalena Maria, Marcelis, Lukas, Chinello, Clizia, Wouters, Jasper, Magni, Fulvio, Alexopoulos, Leonidas, Stas, Marguerite, Boecxstaens, Veerle, Bechter, Oliver, Cattoretti, Giorgio, van den Oord, Joost
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2020
Schlagworte:
Cancer Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053517/
https://ncbi.nlm.nih.gov/pubmed/32057296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.53008
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