Effects of Shikonin on the Functions of Myeloid Dendritic Cells in a Mouse Model of Severe Aplastic Anemia

This study is aimed at investigating the effects of shikonin, a pyruvate kinase M2 (PKM2) inhibitor, on the functions of myeloid dendritic cells (mDCs) in a mouse model of severe aplastic anemia (AA) generated by total body irradiation and lymphocyte infusion. Flow cytometry and qPCR were used to de...

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Publicado en:Mediators Inflamm
Autores principales: Zheng, Mengying, Liu, Bingnan, Shao, Yuanyuan, Hua, Luogang, Fu, Rong, Wang, Huaquan, Wang, Ting, Qi, Weiwei, Shao, Zonghong, Liu, Chunyan
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053458/
https://ncbi.nlm.nih.gov/pubmed/32148443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/9025705
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