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Hinokitiol reduces tumor metastasis by inhibiting heparanase via extracellular signal-regulated kinase and protein kinase B pathway

Heparanase cleaves the extracellular matrix by degrading heparan sulfate that ultimately leads to cell invasion and metastasis; a condition that causes high mortality among cancer patients. Many of the anticancer drugs available today are natural products of plant origin, such as hinokitiol. In the...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Wu, Yueh-Jung, Hsu, Wei-Jie, Wu, Li-Hsien, Liou, Huei-Pu, Pangilinan, Christian Ronquillo, Tyan, Yu-Chang, Lee, Che-Hsin
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053356/
https://ncbi.nlm.nih.gov/pubmed/32132875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.41177
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