SASH1 promotes melanin synthesis and migration via suppression of TGF-β1 secretion in melanocytes resulting in pathologic hyperpigmentation

Dyschromatosis universalis hereditaria (DUH) is an autosomal dominant pigmentary genodermatosis characterized by the presence of patches of hyperpigmentation and hypopigmented macules distributed over the body, with most cases reported in Asia. DUH is a heterogeneous disease and a small portion of p...

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Udgivet i:Int J Biol Sci
Main Authors: Cui, Hongzhou, Guo, Shuping, He, Hongxia, Guo, Huina, Zhang, Yuliang, Wang, Binquan
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053321/
https://ncbi.nlm.nih.gov/pubmed/32174800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.38415
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