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Synthesis and inhibitory activity of N-acetylpyrrolidine derivatives on α-glucosidase and α-amylase

BACKGROUND AND PURPOSE: Carbohydrate hydrolysis enzymes including α-glucosidase and α-amylase are related to type 2 diabetes mellitus. The inhibiting of these enzymes might use for type 2 diabetes mellitus treatment. EXPERIMENTAL APPROACH: N-substituted-acetylpyrrolidine linked with -benzyl- (N-(ben...

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Detalhes bibliográficos
Publicado no:Res Pharm Sci
Main Authors: Sansenya, Sompong, Winyakul, Chankan, Nanok, Kesinee, Phutdhawong, Waya S.
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer - Medknow 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053292/
https://ncbi.nlm.nih.gov/pubmed/32180813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.278711
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