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Spiroindolone Analogues as Potential Hypoglycemic with Dual Inhibitory Activity on α-Amylase and α-Glucosidase

Inhibition of α-amylase and α-glucosidase by specified synthetic compounds during the digestion of starch helps control post-prandial hyperglycemia and could represent a potential therapy for type II diabetes mellitus. A new series of spiroheterocyclic compounds bearing oxindole/benzofuran/pyrrolidi...

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Vydáno v:Molecules
Hlavní autoři: Altowyan, Mezna Saleh, Barakat, Assem, Al-Majid, Abdullah Mohammed, Al-Ghulikah, H.A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6630796/
https://ncbi.nlm.nih.gov/pubmed/31242688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24122342
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