LRR domain of NLRX1 protein delivery by dNP2 inhibits T cell functions and alleviates autoimmune encephalomyelitis

Multiple sclerosis (MS) is a demyelinating inflammatory disease of the central nervous system (CNS), which is a chronic progressive disease and is caused by uncontrolled activation of myelin antigen specific T cells. It has high unmet medical needs due to the difficulty of efficient drug delivery in...

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Bibliographic Details
Published in:Theranostics
Main Authors: Koo, Ja-Hyun, Kim, Do-Hyun, Cha, Donghun, Kang, Min-Jong, Choi, Je-Min
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2020
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053182/
https://ncbi.nlm.nih.gov/pubmed/32194859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43441
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