dNP2-ctCTLA-4 inhibits German cockroach extract-induced allergic airway inflammation and hyper-responsiveness via inhibition of Th2 responses

German cockroaches are major household allergens that can trigger allergic airway inflammatory diseases with sensitive T-cell responses. Although the use of immune modulatory biologics, such as antibodies, to mediate allergic responses has recently been examined, only systemic administration is avai...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Lim, Sangho, Ho Sohn, Jung, Koo, Ja-Hyun, Park, Jung-Won, Choi, Je-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5579505/
https://ncbi.nlm.nih.gov/pubmed/28775364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.107
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