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Kynurenine pathway, NAD(+) synthesis, and mitochondrial function: targeting tryptophan metabolism to promote longevity and healthspan

Aging is characterized by a progressive decline in the normal physiological functions of an organism, ultimately leading to mortality. Nicotinamide adenine dinucleotide (NAD(+)) is an essential cofactor that plays a critical role in mitochondrial energy production as well as many enzymatic redox rea...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Castro-Portuguez, Raul, Sutphin, George L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7053056/
https://ncbi.nlm.nih.gov/pubmed/31954874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2020.110841
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