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A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells

It remains unknown whether H3K4 methylation, an epigenetic modification associated with gene activation, regulates fate determination of the postnatal neural stem and progenitor cells (NSPCs). By inactivating the Dpy30 subunit of the major H3K4 methyltransferase complexes in specific regions of mous...

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Detalles Bibliográficos
Publicado en:J Mol Cell Biol
Main Authors: Shah, Kushani, King, Gwendalyn D, Jiang, Hao
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052987/
https://ncbi.nlm.nih.gov/pubmed/31065682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz036
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