Targeting microtubules sensitizes drug resistant lung cancer cells to lysosomal pathway inhibitors

Oncogene-addicted cancers are predominantly driven by specific oncogenic pathways and display initial exquisite sensitivity to designer therapies, but eventually become refractory to treatments. Clear understanding of lung tumorigenic mechanisms is essential for improved therapies. Methods: Lysosome...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Chin, Tan-Min, Boopathy, Gandhi T. K., Man, Ellen P.S., Clohessy, John G., Csizmadia, Eva, Quinlan, Margaret P, Putti, Thomas, Wan, Seow-Ching, Xie, Chen, Ali, Azhar, Wai, Fhu Chee, Ong, Yan Shan, Goh, Boon-Cher, Settleman, Jeff, Hong, Wanjin, Levantini, Elena, Tenen, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052910/
https://ncbi.nlm.nih.gov/pubmed/32194831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.38729
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