Targeted alpha therapy in a systemic mouse model of prostate cancer - a feasibility study

(225)Ac-PSMA-617 targeted-therapy has demonstrated efficacy in 75-85% of patients; however, responses are not durable. We aimed to establish translatable mouse models of disseminated prostate cancer (PCa) to evaluate effectiveness of (225)Ac-PSMA-617 at various disease stages. Methods: C4-2, C4-2B,...

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Veröffentlicht in:Theranostics
Hauptverfasser: Stuparu, Andreea D., Meyer, Catherine A.L., Evans-Axelsson, Susan L., Lückerath, Katharina, Wei, Liu H., Kim, Woosuk, Poddar, Soumya, Mona, Christine E., Dahlbom, Magnus, Girgis, Mark D., Radu, Caius G., Czernin, Johannes, Slavik, Roger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052903/
https://ncbi.nlm.nih.gov/pubmed/32194823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.42228
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