Clinical and functional significance of CHK1-S, an alternatively spliced isoform of the CHK1 gene, in hepatocellular carcinoma

Alternative splicing plays critical roles in many disease processes and splicing dysregulation is a hallmark of cancer. The different splicing isoforms may have significantly different effects on the malignant progression of cancer. Checkpoint kinase 1 (CHK1) is a serine/threonine kinase and regulat...

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Detaylı Bibliyografya
Yayımlandı:J Cancer
Asıl Yazarlar: Hu, Guanghui, Wang, Shuren, Wang, Yu, Gao, Yang, Zhu, Hongxia, Liu, Mei, Xu, Ningzhi, Wang, Liming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Ivyspring International Publisher 2020
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052871/
https://ncbi.nlm.nih.gov/pubmed/32194790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.39443
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