Antenatal sildenafil citrate treatment increases offspring blood pressure in the placental-specific Igf2 knockout mouse model of FGR

Fetal growth restriction (FGR), where a fetus fails to reach its genetic growth potential, affects up to 8% of pregnancies and is a major risk factor for stillbirth and adulthood morbidity. There are currently no treatments for FGR, but candidate therapies include the phosphodiesterase-5 inhibitor s...

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Gepubliceerd in:Am J Physiol Heart Circ Physiol
Hoofdauteurs: Renshall, L. J., Cottrell, E. C., Cowley, E., Sibley, C. P., Baker, P. N., Thorstensen, E. B., Greenwood, S. L., Wareing, M., Dilworth, M. R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052623/
https://ncbi.nlm.nih.gov/pubmed/31809211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00568.2019
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