The atrial natriuretic peptide (ANP) knockout mouse does not exhibit the phenotypic features of pre-eclampsia or demonstrate fetal growth restriction

The ANP knockout mouse is reported to exhibit pregnancy-associated hypertension, proteinuria and impaired placental trophoblast invasion and spiral artery remodeling, key features of pre-eclampsia (PE). We hypothesized that these mice may provide a relevant model of human PE with associated fetal gr...

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Détails bibliographiques
Publié dans:Placenta
Auteurs principaux: Finn-Sell, Sarah L., Renshall, Lewis J., Cowley, Elizabeth J., Dilworth, Mark R., Wareing, Mark, Greenwood, Susan L., Sibley, Colin P., Cottrell, Elizabeth C.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2016
Sujets:
Short Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898207/
https://ncbi.nlm.nih.gov/pubmed/27238710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2016.04.003
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