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Mechanosensor transient receptor potential vanilloid member 4 (TRPV4) regulates mouse cholangiocyte secretion and bile formation

Mechanosensitive signaling has emerged as a mechanism for the regulation of cholangiocyte transport and bile formation. The mechanical effect of fluid-flow, or shear, at the apical membrane of cholangiocytes regulates secretion through a process involving increases in [Ca(2+)](i) and activation of C...

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Опубликовано в: :Am J Physiol Gastrointest Liver Physiol
Главные авторы: Li, Qin, Kresge, Charles, Boggs, Kristy, Scott, Julie, Feranchak, Andrew
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7052575/
https://ncbi.nlm.nih.gov/pubmed/31760763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00176.2019
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