Signaling through the interleukin-4 and interleukin-13 receptor complexes regulates cholangiocyte TMEM16A expression and biliary secretion

TMEM16A is a Ca(2+)-activated Cl(−) channel in the apical membrane of biliary epithelial cells, known as cholangiocytes, which contributes importantly to ductular bile formation. Whereas cholangiocyte TMEM16A activity is regulated by extracellular ATP-binding membrane purinergic receptors, channel e...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Dutta, Amal K., Boggs, Kristy, Khimji, Al-karim, Getachew, Yonas, Wang, Youxue, Kresge, Charles, Rockey, Don C., Feranchak, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191463/
https://ncbi.nlm.nih.gov/pubmed/32090602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00219.2019
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